Although the incidence of retinal arterial or venous thrombosis is unclear and death does not occur, significant visual impairment is a major problem.  At least 30% of individuals suffering from retinal vascular thrombosis have a blood coagulation protein or platelet defect; some are hereditary and some are acquired. 

Defining the defect will allow one to optimize antithrombotic therapy for preventing another episode, thus preserving sight as much as possible; this is the best way to make sure appropriate therapy can be delivered to decrease, as much as possible, another event.  If the defect is hereditary, appropriate family members should be assessed and, when indicated, treated to potentially prevent the first retinal or other type of thrombosis.

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